FORMATE METABOLISM BY ANIMAL TISSUES
نویسندگان
چکیده
منابع مشابه
Formate Metabolism by Animal Tissues*?
Many studies on the metabolism of formic acid by a variety of animal tissues have shown that an appreciable portion of this substrate is oxidized to carbon dioxide (6-13). Since the initial observation of Battelli (6) and Battelli and Stern (7) on the oxidation in vitro of formate, various uncorrelated attempts have been made to identify the responsible enzymes to explain the mechanism of this ...
متن کاملMetabolism of Propionic Acid in Animal Tissues
The conversion of propionyl coenzyme A to succinyl-CoA involves carboxylation to methylmalonyl-Cob (a), isomerization of methyhnalonyECoA (a) to its enantiomorph methyhnalonylCoA (b), and isomerization of the latter to succinyl-CoA (3). Since methylmalonyl-CoA (a) has recently been shown to have the D configuration (4, 5), the reversible reaction catalyzed by methylmalonyl-CoA racemase will hen...
متن کاملCCXXXIII. METABOLISM OF a-KETOGLUTARIC ACID IN ANIMAL TISSUES
DEWAN [1938] and Adler et al. [1939] reported that certain enzyme preparations obtained from heart muscle bring about a reductive amination of ac-ketoglutaric acid. The hydrogen required in this reaction may be provided from other dehydrogenase systems via coenzyme I or II, especially from the ,-hydroxybutyric and i8ocitric dehydrogenases, according to the schemes: (1) ac-ketoglutaric acid+NH3+...
متن کاملThe metabolism of hypoxanthine desoxyriboside in animal tissues.
Klein (1) has made a detailed investigation of the action of “purine nucleosidase” on the various purine desoxyribosides. He found that preparations of animal tissues which split purine ribosides also split the purine desoxyribosides, yielding the purine base and a reducing sugar. The enzyme preparations were inactivated upon dialysis, but could be reactivated by the addition of arsenate or pho...
متن کاملFormate metabolism in fetal and neonatal sheep.
By virtue of its role in nucleotide synthesis, as well as the provision of methyl groups for vital methylation reactions, one-carbon metabolism plays a crucial role in growth and development. Formate, a critical albeit neglected component of one-carbon metabolism, occurs extracellularly and may provide insights into cellular events. We examined formate metabolism in chronically cannulated fetal...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1957
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)65047-1